A Nutritional Approach to Balancing Inflammation and Energy Production

Published on January 10, 2025

Patients with Myeloproliferative Neoplasms (MPN) often experience symptoms like fatigue, weight fluctuations, and mental fog. But did you know that a carefully planned diet can help? Carla Not, a clinical dietitian specializing in oncology, emphasizes the importance of nutrition in managing these symptoms and improving overall well-being.

 

 

 

 

 

 

 

 

The Power of Anti-Inflammatory Diets 

For MPN patients, an anti-inflammatory diet, such as the Mediterranean diet, is a game changer! It helps reduce chronic inflammation, which can significantly improve symptoms like fatigue and weight gain. Following this diet can make a world of difference. 



The Balance of Omega-3 and Omega-6 

Carla Not highlights the importance of balancing Omega-3 and Omega-6  fatty acids. Too much Omega-6, common in modern diets, can lead to inflammation, so it’s crucial to eat more Omega-3-rich foods. such as sardines, salmon, and mackerel. 



Key Takeaways for MPN Patients 

- Balance Omega-3 and Omega-6: Add more Omega-3-rich foods, like sardines, mackerel and salmon, to reduce inflammation.

- Include Anti-Inflammatory Foods: The Mediterranean diet is a great example of an anti-inflammatory eating pattern.

- Intermittent Fasting (14-Hour Fast): Intermittent fasting, particularly the 14-hour fast, can reduce inflammation and promote metabolic health. During fasting periods, it's best to drink water, herbal teas, vegetable broth, green tea, or black coffee (without sugar or milk) to stay hydrated and support gut health.

- Gut Health and Mental Wellbeing: A healthy gut microbiome is crucial for both physical and mental health. Fermented food such as Kéfir (sheep and goat), Kvass (fermented beetroot). 

 

This meal plan is tailored for MPN patients, combining delicious recipes with the power of anti-inflammatory foods to help manage symptoms and boost overall wellness. 

 

Recipes to Improve Your Quality of Life 

Here are some delicious recipes that follow the Mediterranean and anti-inflammatory diet principles, specially designed for MPN patients:

 

1. Salmon with Quinoa and Roasted Vegetables

 

This dish is packed with Omega-3 fatty acids from salmon, which helps reduce inflammation. Quinoa offers plant-based protein, and the roasted veggies provide essential vitamins and fiber! 

 

Ingredients:

- 1 small salmon fillet

- 1 cup quinoa

- Zucchini, bell peppers, carrots (or your favorite veggies)

- Olive oil, lemon, salt, and pepper

 

Instructions:

1. Cook quinoa as per the package.

2. Season salmon with olive oil, lemon, salt, and pepper. Bake at 180°C (350°F) for 12-15 minutes.

3. Roast vegetables with olive oil, salt, and pepper for 25 minutes.

4. Serve the salmon over quinoa with roasted veggies. Enjoy! 

 

2. Sardine and Avocado Salad 

 

Sardines are a powerhouse of Omega-3 and are highly recommended for their anti-inflammatory benefits and low mercury content. 

 

Ingredients:

- 1 can of sardines (in olive oil)

- 1 avocado, sliced

- Mixed greens (spinach, arugula, etc.)

- Olive oil, lemon juice, salt, and pepper

 

Instructions:

1. Place sardines and avocado slices on mixed greens.

2. Drizzle with olive oil, lemon juice, salt, and pepper. A simple, healthy meal in minutes! 

 

3. Chickpea and Spinach Stew 

 

This plant-based stew is rich in fiber, supporting gut health and mental well-being—vital for managing MPN symptoms. 

 

Ingredients:

- 1 can chickpeas

- 2 cups spinach

- 1 garlic clove, minced

- 1 onion, chopped

- Olive oil, cumin, salt, and pepper

 

Instructions:

1. Sauté garlic and onion in olive oil until soft.

2. Add chickpeas, cumin, salt, and pepper. Cook for a few minutes.

3. Stir in spinach and let it simmer for 10 minutes. Serve hot!

 

These nutritious recipes are based on expert advice from Carla Not, an expert in nutrition, at the 4th MPN Spring Symposium, designed to help MPN patients feel their best. Ready to take charge of your health with these easy, wholesome meals? Let’s get cooking!